Unscrambler Online 2.2

A revolutionary, plug 'n' play product designed for end-users across industry verticals, the new Unscrambler Online comes with unique features that allow it to make effective on-line predictions and classifications, to monitor processes and ensure quality control with spectroscopic measurements.

The Unscrambler Online enables full utilization of PLS-R and PCR models for prediction, PLS-R, PCR and PCA for classification developed in The Unscrambler®. The use of Unscrambler Online results in effective application of multivariate statistical approaches in process & quality control, research and development.

The Unscrambler Online enables the complete exploitation of the PLS and PCA models developed in The Unscrambler® software. The result is effective application in process control, quality control, research and development.

Unscrambler Online

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Product Highlights

Prediction through Polling

Selects and uploads PLS-R and PCA models developed in The Unscrambler®
Supports
- All pretreatments and combination of pretreatments available in The Unscrambler 9.6 and earlier versions.
- Extended Multiplicative Scatter Correction data (EMSC)
- Simultaneous online prediction on multiple The Unscrambler® models
- JCAMP-DX,GRAMS & BFF3 data import file formats
- Reduced model file size with new format option called "Micro model". This choice, while running a PCR or PLS,saves fewer matrices on file, thus reducing the model file size. The micro models can be used only for prediction.
Displays and updates results in Excel format on screen. Prediction Uncertainty, Sample Residual and Leverage are available as part of prediction results.
Prediction can be performed for Optimal PC as well as for any other PC set by the user
Elaborate result outputs are given in EXCEL/XML/HTML or ASCII formats and salient information in Result Summary file

Classification through Polling

Select and upload PCA models developed in The Unscrambler®
Supports
- All pretreatments and combination of pretreatments available in The Unscrambler 9.6 and earlier versions.
- Simultaneous online classification on multiple The Unscrambler® models
Displays and updates results in Excel format on screen. Scores, Sample Residual and Leverage are available as part of classification results
Elaborate result outputs are given in EXCEL/XML/HTML or ASCII formats and salient information in Result Summary file

Salient Features

The features incorporated in the Unscrambler Online enable users to use Unscrambler models.

Easy Configuration. The software provides easy-to-use user interfaces. The user need not possess programming skills to configure and create an operation service. A saved configuration service can be viewed, edited and used at any time.

File Polling . The software enables users to predict or classify samples online at regular or user defined intervals through UI, by using previously developed The Unscrambler® models. The Polling mechanism, in effect, utilizes JCAMP-DX,GRAMS & BFF3 input data formats measured by spectroscopic instruments.

Auto Pretreatments supported . The software supports all the auto pretreatments/ transformations used in The Unscrambler® while developing the model, like Smoothing, Normalizations, Baseline Corrections, Derivatives, Multiplicative Scatter Correction (MSC), and Standard Normal Variate (SNV). This ensures that the calibration models and prediction samples have the same data pretreatments.

Multiple Calibration Model Selection The software supports simultaneous online prediction on multiple The Unscrambler® models. The user can compare prediction results using different variable range, number of optimum PC, and data pre-treatments. A configuration service is also allowed to include different type of calibration models, PLS1, PLS2, and PCR.

Classification The software facilitates SIMCA operation for online classification with The Unscrambler® PCA models. Scores, Sample Residual and Leverage are available as part of classification results

Result Display and Save The software displays and updates results in Excel format on screen.The excel format can be saved as a Microsoft Excel file for further reference and analysis. Prediction Uncertainty, Sample Residual and Leverage are available as part of prediction results. Scores, Sample Residual and Leverage are available as part of classification results.

Security and Traceability The software authenticates Username and Password. Batch name and date

indicate and identify the operation and measurements as per the 21 CFR Part 11 compliance requirement. Model and measurement information is kept in the configuration service.

Industry Verticals

The Unscrambler Online helps optimize product processes in the following verticals,

Pharmaceuticals
Food Manufacturing
Environment
Petroleum
Biotechnology
Chemicals
Polymer & Petrochemicals
Paper

Industry Applications

The software can be used effectively across industry verticals to,

Predict the composition of different constituents in the final mixture
Predict contaminant values of pollutants in the product and process
Constantly identify raw input materials and output quality
Monitor blending, drying, dissolution and other processes

Benefits

A practical and cost-effective software, organizations can experience a multitude of benefits by using the Unscrambler Online. Help streamline operations and regulatory requirements.

Real-time measurement in the product or process

Real-time measurements using the software facilitate online prediction and classification of the process parameters and product qualities. This helps adjust the process / production parameters like Temperature, RPM in real time, in response to the results.

Process Analytical Technologies

The real-time Prediction and Classification features inherent in Unscrambler Online bring companies one step further in mastering their process and product control.

Quantitative Analysis and Quality Control

The application helps release / reject raw materials and/or finished products in minimal time. This reduces the need to wait for results from the Quality Control laboratory and aids in enhancing the Quantitative Analysis and Quality Control processes.

Trace Results & Models

The inherent features, namely User Log-in and Time Stamped Reports help users keep track of the online prediction results. The features ensure that production process parameters are in compliance with standards laid down by regulatory authorities.

Standardize & streamline formulations

The software ensures that formulations contain a standardized & streamlined definition across the organization.